Search for a Cure
Search for a Cure
CROI 2013: Gene Therapy Studies Show Potential for HIV Control without Drugs
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- Category: Search for a Cure
- Published on Wednesday, 10 April 2013 00:00
- Written by Gus Cairns
Modified immune cells that make their own fusion inhibitors reduce levels of HIV-like virus and resisted infection in animal and test tube studies, researchers reported at the 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) last month in Atlanta.
CROI 2013: Antiretroviral Therapy Intensification plus IL-7 Does Not Reduce HIV Reservoir
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- Category: Search for a Cure
- Published on Wednesday, 10 April 2013 00:00
- Written by Liz Highleyman
An intensive antiretroviral regimen containing raltegravir (Isentress) and maraviroc (Selzentry) plus the immune-modulator interleukin 7 (IL-7) was unable to decrease the amount of residual HIV in resting CD4 T-cells, investigators with the ERAMUNE-01 trial reported at the recent 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) in Atlanta.
CROI 2013: Functional Cure of HIV-infected Infant after Early ART [VIDEO]
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- Category: Search for a Cure
- Published on Wednesday, 20 March 2013 00:00
- Written by Gregory Fowler
The big news on the opening day of the 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) was a report about an infant with HIV who started combination antiretroviral treatment very early and now shows no evidence of replication-competent virus. "We equate this to our Berlin Patient," said Deborah Persaud from Johns Hopkins University School of Medicine. "It could get us on the road to a cure for HIV-infected children."
French Cohort of HIV+ People Treated Early Appear to Control Virus
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- Category: Search for a Cure
- Published on Monday, 25 March 2013 00:00
- Written by Liz Highleyman
A group of French HIV patients who started antiretroviral therapy (ART) during the earliest stage of infection appear to be controlling the virus despite prolonged treatment interruption, according to a recent report in PLoS Pathogens. While the findings do not represent a cure, they may offer insight to help certain people with HIV achieve a "functional cure," or periods off treatment without disease progression.
CROI 2013: Can HIV Elite Controllers Benefit from Antiretroviral Treatment?
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- Category: HIV Treatment
- Published on Friday, 15 March 2013 00:00
- Written by Liz Highleyman
Elite controllers -- people who naturally maintain undetectable viral load without antiretroviral therapy (ART) -- experienced decreased levels of HIV genetic material and reductions in markers of inflammation and immune activation after starting experimental treatment, according to study findings presented at the 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) last week in Atlanta.
More Articles...
- CROI 2013: Zinc Finger Gene Therapy Leads to Durable T-Cell Recovery, Sangamo Says
- CROI 2013: Early Antiretroviral Therapy May Reduce HIV Reservoir Size [VIDEO]
- CROI 2013: HIV Treatment for Children Safe and Highly Effective without Laboratory Monitoring
- CROI 2013: Very Early Antiretroviral Treatment Limits the Size of HIV Reservoir
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