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ICAAC 2013: CD4 Cell Gene Therapy May Enable Functional Control of HIV Off Treatment

Two people whose CD4 T-cells were modified to make them resistant to HIV experienced substantial CD4 cell gains and were able to maintain viral suppression after interruption of antiretroviral therapy (ART), according to a late-breaker presentation at the 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2013) this week in Denver.

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IAS 2013: Intensive ART During Primary HIV Infection Lowers Viral Reservoir

Starting intensive antiretroviral therapy (ART) with a 5-drug regimen during the earliest stages of HIV infection can result in lower levels of virus in resting T-cell reservoirs, leading to improved immune function and potentially a better chance at a functional cure, according to studies presented at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) this month in Kuala Lumpur.

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IAS 2013: The Future of HIV Cure Research [VIDEO]

Research towards a cure for HIV was a key theme of the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) last month in Kuala Lumpur, as well as a 2-day IAS pre-conference. While hesitant to make firm predictions, experts offered some cautious opinions on the future of cure research.

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HIV+ Boy Dies After HIV-resistant Stem Cell Transplant for Leukemia

A 12-year-old HIV positive boy with acute lymphoblastic leukemia died earlier this month due to graft-versus-host disease complications after undergoing an experimental cord blood transplant in April from a donor with the CCR5-delta-32 (CCR5-Δ-32) mutation, which makes cells resistant to HIV entry, the University of Minnesota announced this week.

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IAS 2013: Kick, Kill, Contain -- Researchers Examine 3 Possible Steps in a Cure for HIV

The 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) this month in Kuala Lumpurfeatured a special 2-day symposium on progress towards a cure for HIV, and also featured a number of presentations on possible approaches towards a cure in the main body of the conference.

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