CROI 2014: Boston Patients Experience HIV Rebound after Stem Cell Transplants

HIV has re-emerged in 2 Boston men who underwent experimental antiretroviral therapy (ART) interruption after receiving bone marrow stem cell transplants for cancer treatment, Timothy Henrich reported at the 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) this week in Boston. These cases suggest that a functional cure for HIV will be difficult to achieve if even a small amount of residual virus remains in the body.

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CROI 2014: Protected T-cells Persist and Proliferate in HIV Gene Therapy Study

Genetically modified CD4 T-cells lacking CCR5 co-receptors reach high levels in the body and are resistant to HIV infection, potentially enabling people to maintain a low viral load while off antiretroviral therapy (ART), according to the latest reports from studies evaluating Sangamo Biosciences' SB-728-T zinc finger gene therapy technology.

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CROI 2014: HIV Rebounds in Boston Bone Marrow Transplant Patients [VIDEO]

Detectable HIV has returned in 2 Boston stem cell transplant recipients who for a time appeared to be controlling the virus during antiretroviral treatment interruption, Timothy Henrich from Brigham and Women's Hospital reported at the reported at the 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) this week in Boston.

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CROI 2014: HIV Cure News from the Retrovirus Conference

The 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) this week in Boston featured updates related to various aspects of the search for a cure for HIV.